I- I-Systemic Contact Dermatitis (Systemic contact dermatitis) ibhekisa kwimeko yolusu apho umntu othe waziva evezwe ngesikhumba kwi-allergen aya kuthi emva koko asabele ngokuqatha kwaloo nto ifanayo ngendlela eyahlukileyo. Iyenzeka kwi-allergener kubandakanya isinyithi, amayeza, kunye nokutya.